Journal article
CAP protein superfamily members in Toxocara canis
AJ Stroehlein, ND Young, RS Hall, PK Korhonen, A Hofmann, PW Sternberg, A Jabbar, RB Gasser
Parasites and Vectors | BMC | Published : 2016
Abstract
Background: Proteins of the cysteine-rich secretory proteins, antigen 5 and pathogenesis-related 1 (CAP) superfamily are recognized or proposed to play roles in parasite development and reproduction, and in modulating host immune attack and infection processes. However, little is known about these proteins for most parasites. Results: In the present study, we explored CAP proteins of Toxocara canis, a socioeconomically important zoonotic roundworm. To do this, we mined and curated transcriptomic and genomic data, predicted and curated full-length protein sequences (n = 28), conducted analyses of these data and studied the transcription of respective genes in different developmental stages of..
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Grants
Awarded by Australian Research Council
Funding Acknowledgements
The present study was funded by the Australian Research Council (ARC), the National Health and Medical Research Council of Australia (NHMRC) and the Wellcome Trust (Pathfinder) (RBG). NDY is a NHMRC Career Development Fellow (CDF). AJS is a recipient of a Melbourne International Research Scholarship (MIRS) and a Melbourne International Fee Remission Scholarship (MIFRS) from The University of Melbourne. Funding bodies had no role in the design of the study or collection, analysis or interpretation of data, or in writing the manuscript.